The Extractives of Cupressaceae Trees and Their Bioactivities

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  • ヒノキ科樹木の抽出成分と生理活性
  • ヒノキカ ジュモク ノ チュウシュツ セイブン ト セイリ カッセイ

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The present state of our knowledge on the chemical structures of new compounds, chemotaxisonomic GC-MS analysis and bioactivities of the constituents from Cupressaceae trees, are reviewed with particular reference since 1991. Cupressaceae trees are amongst those that are rich sources of terpenoid compounds. There are a large number of reports about GC-MS analysis of volatile terpenes in leaves. The essential oils and extractives from Cupressaceae trees have a variety of bioactivities, e. g. antimicrobial, insecticidal, miticidal activities, the relaxant effects against a psychological stress, etc. It is worthy of special mention that β-thujaplicin (hinokitiol) has been reported as having a variety of bioactivities, e.g. antignawing, antimicrobial, insecticidal, miticidal, parasiticidal, antimetalloprotease, antityrosinase, antioxidative activities, and scavenging activity against active oxygen, and inhibitory effect on UV-B-induced apotosis. With the development of many sophisticated spectral instruments and chromatographic techniques, isolation and structural elucidation of bioactive compounds in the extracts have become quite facilitation, subsequently to the accumulation of the knowledge of structure-bioactivity relationships. Thus, as research facilities are great improved, on the basis of bioactivity and the chemical structure of constituents in the extract, the exploitation of high valued utilization of the Cupressaceae trees, especially Chamaecyparis obtusa known as one of the most important timber in Japan, should be expected.

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