Is Whole Body Bone Mineral Density Measured by the Dual Energy X- ray Absorptiometry Applied to Evaluate Risk of Osteoporosis among Japanese Adult Females?

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  • Sakai Yumiko
    Fukuoka Health Promotion Center | Fukuoka Health Promotion Foundation
  • Koike George
    Fukuoka Health Promotion Center | Fukuoka Health Promotion Foundation
  • Numata Makoto
    Fukuoka Health Promotion Center | Fukuoka Health Promotion Foundation
  • Taneda Kiyoshi
    Fukuoka Health Promotion Center | Fukuoka Health Promotion Foundation
  • Jingu Sumie
    Fukuoka Health Promotion Center | Fukuoka Health Promotion Foundation

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Other Title
  • 日本人成人女性において二重エネルギー X線吸収法（dual energy X-ray absorptiometry）による 全身骨密度値で骨粗鬆症リスクは評価できるか?
  • ニホンジン セイジン ジョセイ ニ オイテ 2ジュウ エネルギー Xセン キュウシュウホウ dual energy X ray absorptiometry ニ ヨル ゼンシン コツミツドチ デ コツソショウショウ リスク ワ ヒョウカ デキル カ

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Abstract

To measure whole body fat accurately, the dual energy X-ray absorptiometry (DXA) is widely utilized. Simultaneously, bone mineral density (BMD) of the whole body can also be measured. BMD is one of important information to diagnose osteoporosis. However, it is not established to use whole body BMD for this diagnosis. It is recommended that lumbar and/or hip BMD should be used for diagnosing osteoporosis by the guideline for prevention and treatment of osteoporosis. Although it is possible to measure whole body BMD and lumbar and/or hip BMD separately at the same visit, it is inevitable to expose patients to more X-ray. Therefore, an aim of this study is to elucidate the relationship between whole body BMD and lumbar BMD to find the cut off point of whole body BMD for screening of osteoporosis. Two hundred and thirty six Japanese adult females were ascertained to this study. Whole body BMD and lumbar BMD of each subject were measured with the use of Delphi W (Hologic, USA). One hundred and sixty five subjects were judged as possible osteoporosis (less than 80% of young adult mean (YAM) of lumbar BMD and/or definite fracture of lumbar vertebras). The cut off point of whole body BMD for screening possible osteoporosis was estimated by receiver operated characteristic (ROC) analysis. The cut off point of whole body BMD was 84% of YAM, equivalent to 80% of YAM of lumbar BMD, with the following sensitivity and specificity (0.84 and 0.79, respectively), indicating that whole body BMD could be used for screening osteoporosis.

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  • 福岡醫學雜誌

    福岡醫學雜誌 101 (4), 69-74, 2010-04-25

    Fukuoka Medical Association

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