A Case of Metastatic Osteosarcoma Developed Pneumothorax after Chemotherapy

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A case of osteosarcoma arising in the left humerus of an 18-year-old man associated with the congenital deficiency of corps callosum is presented. He developed spontaneous serial pneumothorax after the combination chemotherapy of Adriamycin (ADM) and cisplutinum (CDDP). The patient managed with tube thoracostomy in each event, and recovered. The mechanism of spontaneous pneumothorax is not completely understood, but it will be appropriate to consider these findings in relation to the rapid regression of the pulmonary metastatic lesion following chemotherapy.

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