Pathology of the toxic action of ricin

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  • Funatsu Gunki
    Laboratory of Biochemistry, Faculty of Agriculture, Kyushu University
  • Funatsu Masaru
    Laboratory of Biochemistry, Faculty of Agriculture, Kyushu University

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  • リシンの毒作用に関する病理学的研究
  • リシン ノ ドク サヨウ ニ カンスル ビョウリガクテキ ケンキュウ

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A pathological study on the toxic action of ricin in rabbits was carried out. As a result, the body weight decreased and the number of leucocytes increased, while the number of erythrocytes and hemoglobin value remained unchangeable. Anatomically, hyperemia, swelling and necrosis of varlous organs, especially the damage of the liver were observed.

箆麻子の毒性蛋白質リシンを投与した家兎は著しい体重の減少および白血球の増加が見られた.一方,赤血球数およびヘモグロビン値にはほとんど変化はないが,各臓器の充血,腫脹ならびに実質細胞壊死が認められ,とくに肝細胞壊死が最も強かつた.

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