Myalgic encephalomyekitis/chronic fatigue syndrome (ME/CFS) ― Recent aspects ―

DOI
  • Kuratsune Hirohiko
    Department of Metabolism, Endocrinology, Osaka City University Graduate School of Medicine ; Division of Health Science, Osaka University Graduate School of Medicine ; Fatigue Mental Health Check Center (FMCC) Inc.

Bibliographic Information

Other Title
  • 筋痛性脳脊髄炎/慢性疲労症候群（ME/CFS）―最近の知見―

Description

<p>We describe here our results of epidemiological survey for fatigue in Japan, and our recent findings found in chronic fatigue syndrome (CFS) patients. In 1999, our epidemiological survey of 3,015 Japanese people revealed that 35.6% of them had chronic fatigue and 16.8% had a deterioration of daily physical activities. Eight people (0.26%) were diagnosed as CFS according to CDC 1994 criteria. Our recent studies revealed that the existence of neuroinflammation in patients with CFS by the positron emission tomography. We also found that CFS patients exhibited significant differences in intermediate metabolite concentrations in the tricarboxylic acid and urea cycles, and that the identification of actin network proteins in circulating extracellular vesicles were useful as the blood biomarkers for CFS.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390290780263365376
  • NII Article ID
    130008142559
  • DOI
    10.15082/jsnt.38.3_164
  • ISSN
    21897824
    09168443
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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