A Case of Portal Vein Thrombosis After Hepatic Injury for Which Edoxaban Was Effective

Yokosawa Tomoki, Ueki Shunsuke, Onodera Yu, Suzuki Hiroshi, Hoshida Toru

doi:10.11231/jaem.41.5_315

<p>The patient was a 69-year-old woman who sustained injury in a traffic accident, when the car she was driving collided with a telephone pole, and she was transferred to our hospital with precordial pain and abdominal pain. Abdominal CT showed injury of the medial segment of the liver, with active extravasation. While she was on the CT table, her blood pressure dropped and transcatheter arterial embolization was performed to stabilize the vital signs. A CT performed 14 days after the injury showed portal vein thrombosis, and another performed 21 days after the injury showed expansion of the thrombus. Therefore, oral administration of edoxaban was initiated. A CT on the 10th day after the initiation of oral edoxaban administration showed reduction in the size of the thrombus, and on the 56th day, complete disappearance of the thrombus was confirmed, and oral edoxaban was discontinued. No recurrence of the portal vein thrombosis has been observed during follow-up. There are few reports of portal vein thrombosis after liver injury, and there is no established standard therapy for portal vein thrombosis. In recent years, the efficacy of direct-acting oral anticoagulants for portal vein thrombosis has been reported, and in our case reported here, oral administration of edoxaban completely eliminated the thrombus.</p>

A Case of Portal Vein Thrombosis After Hepatic Injury for Which Edoxaban Was Effective

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