Experience of Complete Autologous Fibrin Glue in Spine Surgery

DOI
  • Sasaki Haruo
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Miyake Atsushi
    The Department of Orthopaedic Surgery, National Defense Medical College The Department of Orthopaedic Surgery, International Goodwill Hospital
  • Yasuda Akimasa
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Kitamura Kazuya
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Teramoto Hiroaki
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Amano Shota
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Endo So
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Imai Taisuke
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Kurita Yohei
    The Department of Orthopaedic Surgery, National Defense Medical College
  • Chiba Kazuhiro
    The Department of Orthopaedic Surgery, National Defense Medical College

Bibliographic Information

Other Title
  • 脊椎手術における全自己フィブリン糊の使用経験

Search this article

Abstract

<p>Introduction: Commercially available allogenic fibrin glue is commonly used in daily practice. It is made from pooled human plasma and bovine aprotinin. It, therefore, carries risks of viral infection, allergic reaction, and prion transmission. In contrast, complete autologous fibrin glue (CAFG), made by CryoSeal® System, has no such risks because it is made from patient's own blood only.</p><p>Case Report: We used CAFG in three patients with intradural tumors. Autologous cryoprecipitate and thrombin were extracted from patients' own blood donation and applied on the sutured dura mater with polyglycolic acid sheet after the removal of tumors. One patient had serous discharge from the drain tube and complained of headache immediately after surgery, which got resolved spontaneously. There was no apparent CSF leakage detected on postoperative MRI in all patients.</p><p>Conclusions: CAFG is a safe and potent alternative for commercially available allogenic fibrin glue.</p>

Journal

  • Journal of Spine Research

    Journal of Spine Research 13 (2), 137-143, 2022-02-20

    The Japanese Society for Spine Surgery and Related Research

Keywords

Details 詳細情報について

Report a problem

Back to top