The Comparison of Human Immunodeficiency Virus Type 1 Transmission between Couples through Blood or Sex in Central China
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- Yang Rong-Rong
- Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, PR China
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- Gui Xien
- Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, PR China
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- Benoit Jean-Luc
- Section of Infectious Diseases, University of Chicago, USA
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- Xiong Yong
- Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, PR China
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Abstract
<p>To examine whether there are any differences in the rates of HIV-spousal transmission between those who have acquired the virus through blood or through sex in central China. A total of 650 HIV-infected individuals were enrolled, 420 of them were either former commercial plasma donors or recipients of blood (blood transmission group [BTG]), and 230 had acquired HIV infection through sex (sex transmission group [STG]). The spousal transmission rate of HIV was 2% per year (94/420, 11.2 years) in BTG and 8.9% per year (115/230, 5.6 years) in STG. There was a significantly higher transmission rate of HIV through male-to-female (11.7% per year, 84/128, 5.6 years) than through female-to-male (5.4% per year, 31/102, 5.6 years, P<0.05) in STG, but there was no significant gender based differences in BTG. In BTG, all HIV-1 tested were subtype B', while in STG, HIV-1 tested were predominantly subtypes CRF01_AE or CRF07_BC. Our results show that the HIV-spousal transmission rate was higher in STG than in BTG, and that there was a higher rate through male-to-female than female-to-male in STG.</p>
Journal
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 63 (4), 283-285, 2010-07-30
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
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Details 詳細情報について
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- CRID
- 1390291767802680320
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- NII Article ID
- 40017214361
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- NII Book ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL BIB ID
- 10766148
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed