Characterization of SCCmec types and antibacterial susceptibility patterns of methicillin-resistant Staphylococcus aureus in southern Iran

DOI Web Site Web Site
  • Japoni Aziz
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Jamalidoust Marzieh
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Farshad Shohrah
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Ziyaeyan Mazyar
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Alborzi Abdolvahab
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Japoni Sara
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran
  • Rafaatpour Norradin
    Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Iran

書誌事項

タイトル別名
  • Characterization of SCC<i>mec</i> Types and Antibacterial Susceptibility Patterns of Methicillin-Resistant <i>Staphylococcus aureus</i> in Southern Iran

この論文をさがす

抄録

<p>A total of 156 methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients hospitalized in southern Iran were tested for staphylococcal cassette chromosome mec (SCCmec) types and antibacterial susceptibility patterns between May 2008 and May 2009. Type III SCCmec was the most prevalent (116, 74.3%), followed by mec types A (147 bp only; 11, 7.1%), IVa (8, 5.1%), IVc (7, 4.5%), IVd and V (4, 2.6%), and II (1, 0.6%). Class A mec and type III ccr and mec complexes were also predominant. All isolates were found to be sensitive to vancomycin, teicoplanin, linezolid, quinupristin-dalfopristin, mupirocin, and fusidic acid. However, reduced sensitivity of these MRSA isolates to other antibiotics, including rifampin, co-trimoxazole, clindamycin, cephalexin, tetracycline, ciprofloxacin, erythromycin, and gentamicin, was also observed. The predomination of type III SCCmec could be due to the antibiotic pressure which facilitated its clonal selection and dissemination. The present findings are indicative of the existence of community-acquired types (IV, V) in the hospitals studied, therefore comprehensive and periodic control measures and rational prescription of appropriate antibiotics are highly recommended to reduce antibiotic resistance.<tt> </tt></p>

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ