Evaluation of the adsorption of interleukin-6 with “Hemofeel CH-1.8W” hemofilters

DOI Web Site
  • Okazaki Tetsuya
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Ikeda Takayuki
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Senno Yukiko
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Suzuki Tadashi
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Kibayashi Takuya
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Niibe Tomoko
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Nishihata Junzi
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Ishikawa Atsushi
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Miyashita Makoto
    Department of Clinical Engineering, Kyoto Daiichi Red Cross Hospital
  • Nakanouchi Tsuneyuki
    Department of Nephrology and Blood Purification, Kyoto Daiichi Red Cross Hospital

Bibliographic Information

Other Title
  • ヘモフィールCH-1.8WのIL-6吸着性能の評価
  • ヘモフィール CH-1.8W ノ IL-6 キュウチャク セイノウ ノ ヒョウカ

Search this article

Description

<p>We evaluated the interleukin (IL)-6 adsorption ability of the polymethyl methacrylate (PMMA) hemofilter “Hemofeel CH-1.8W” (Toray Industries, Inc.), which has been used clinically since October 2013. 【Subjects】 We assessed 10 patients who received continuous renal replacement therapy (CRRT) with Hemofeel CH-1.8W whose IL-6 levels were ＞1,000pg/mL at 15min after the start of CRRT. 【Methods】 We measured IL-6 clearance at 15min, 1h, 24h and 48h after therapy commencement. 【Results】 Mean IL-6 clearance (mL/min) was 41.95±7.70 at 15min, 21.50±10.11 at 1h, 8.67±2.67 at 24h, and 13.34±16.77 at 48h. 【Conclusions】 IL-6 clearance was reduced significantly at 24h and 48h. These data suggest that the filter should be changed every 24h to keep its high adsorption performance.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top