Diagnostic Criteria for Acute-on-Chronic Liver Failure and Related Disease Conditions in Japan
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- Mochida Satoshi
- Department of Gastroenterology & Hepatology, Saitama Medical University
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- Nakayama Nobuaki
- Department of Gastroenterology & Hepatology, Saitama Medical University
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- Terai Shuji
- Division of Gastroenterology & Hepatology, Graduate School of Medical and Dental Sciences, Niigata University
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- Yoshiji Hitoshi
- Department of Gastroenterology, Nara Medical University
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- Shimizu Masahito
- Department of Gastroenterology, Gifu University Graduate School of Medicine
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- Ido Akio
- Digestive and Life-Style Diseases, Department of Human and Environmental Sciences, Kagoshima University Graduate School of Medical and Dental Sciences
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- Inoue Kazuaki
- Department of Gastroenterology, International University of Health and Welfare
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- Genda Takuya
- Department of Gastroenterology, Juntendo University Shizuoka Hospital
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- Takikawa Yasuhiro
- Division of Hepatology, Department of Internal Medicine, Iwate Medical University
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- Takami Taro
- Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine
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- Kato Naoya
- Department of Gastroenterology, Graduate School of Medicine, Chiba University
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- Abe Masanori
- Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine
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- Abe Ryuzo
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine
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- Inui Ayano
- Department of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital
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- Ohira Hiromasa
- Department of Gastroenterology, Fukushima Medical University School of Medicine
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- Kasahara Mureo
- Transplantation Center, National Center for Child Health and Development
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- Chayama Kazuaki
- Collaborative Research Laboratory of Medical Innovation, Hiroshima University
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- Hasegawa Kiyoshi
- Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, University of Tokyo
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- Tanaka Atsushi
- Department of Medicine, Teikyo University School of Medicine
Bibliographic Information
- Other Title
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- わが国におけるacute-on-chronic liver failure（ACLF）とその関連病態の診断基準
- ワガクニ ニ オケル acute-on-chronic liver failure (ACLF)ト ソノ カンレン ビョウタイ ノ シンダン キジュン
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Abstract
<p>In 2018, the Intractable Hepato-Biliary Disease Study Group of Japan proposed that patients with cirrhosis and a Child-Pugh score of 5-9 be diagnosed as having ACLF if deterioration of liver function, defined by serum bilirubin level and prothrombin time, develops within 28 days after an acute insult. Disease severity would be classified into four grades depending on the extent of deterioration in organ function. This Study Group has since performed an annual nationwide survey of patients with ACLF who were diagnosed according to the proposed diagnostic criteria as well as those with conditions related to ACLF. Univariate and multivariate analyses revealed that the proposed diagnostic criteria were useful for identifying cirrhotic patients with an unfavorable outcome following an acute insult. Consequently, the Study Group determined that the proposed diagnostic criteria be formally used in both clinical practice and research.</p>
Journal
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- Kanzo
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Kanzo 63 (5), 219-223, 2022-05-01
The Japan Society of Hepatology
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Details 詳細情報について
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- CRID
- 1390292041052488704
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 032144765
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
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- Abstract License Flag
- Disallowed
