Diagnostic Accuracy of Transperineal MRI-Ultrasound Fusion Biopsy at the Introduction Period

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  • HATTORI Yuto
    The Department of Urology, Kyoto University Hospital
  • KONO Jin
    The Department of Urology, Kyoto University Hospital
  • YOSHINO Takayuki
    The Department of Urology, Kyoto University Hospital; The Department of Urology, Faculty of Medicine, University of Tsukuba
  • MASUI Kimihiko
    The Department of Urology, Kyoto University Hospital
  • SATO Takuma
    The Department of Urology, Kyoto University Hospital; The Department of Urology, Tohoku University School of Medicine
  • KASHIMA Soki
    The Department of Urology, Kyoto University Hospital; The Department of Urology, Akita University Graduate School of Medicine
  • SANO Takeshi
    The Department of Urology, Kyoto University Hospital
  • GOTO Takayuki
    The Department of Urology, Kyoto University Hospital
  • SAWADA Atsuro
    The Department of Urology, Kyoto University Hospital
  • AKAMATSU Shusuke
    The Department of Urology, Kyoto University Hospital
  • KOBAYASHI Takashi
    The Department of Urology, Kyoto University Hospital
  • INOUE Takahiro
    The Department of Urology, Kyoto University Hospital; The Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine
  • OGAWA Osamu
    The Department of Urology, Kyoto University Hospital

Bibliographic Information

Other Title
  • 経会陰前立腺MRI-TRUS融合画像ガイド下生検の導入期における診断精度の検討
  • ケイ エイン ゼンリツセン MRI-TRUS ユウゴウ ガゾウ ガイド カセイケン ノ ドウニュウキ ニ オケル シンダン セイド ノ ケントウ

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Description

Magnetic resonance imaging (MRI) ultrasound fusion biopsy is becoming popular owing to the better detection rate of clinically significant prostate cancer (csPCa). We retrospectively evaluated the accuracy of MRI-targeted biopsy during the period of introduction at a single academic center by comparing findings of its specimen and whole-mount histopathology. Between June 2018 and January 2021, 106 transperineal MRI-ultrasound fusion biopsies using BioJet software were performed. Among the cases, 15 subsequently underwent robotic-assisted laparoscopic radical prostatectomy and were eligible for analysis. This study included all regions of interest (ROIs) with a Prostate Imaging Reporting and Data System v2 category of 3 or greater on pre-biopsy MRI．For each lesion, grade group of MRI-targeted biopsy specimens and prostatectomy specimens were compared. From a total of 25 ROIs identified among 15 males, csPCa was found in 21 (84%) of the concordant locations of prostatectomy specimens. However, MRI-targeted biopsy could diagnose csPCa in only 12 (48%) of them. In the csPCa undetected group, the ROI volume was significantly smaller (median volume 0.23 ml vs 0.40 ml, p＝0.03). We also found that in cases where PCa was not detected through MRI-targeted biopsy, the biopsy sample length was significantly shorter (median length 9 mm vs 17 mm, p＝0.01). Our data suggest that failure of detecting PCa in MRI-targeted biopsy could be due to technical errors at the introduction period of the technique. A sufficient sampling length of 10 mm or more is desirable, especially for small lesions.

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  • 泌尿器科紀要

    泌尿器科紀要 68 (4), 99-105, 2022-04-30

    泌尿器科紀要刊行会

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