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Immune Thrombocytopenia Associated with Pembrolizumab
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- Yoshimura Shiori
- Department of Nephrology, Yokohama Minami-Kyousai Hospital
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- Tajika Kenji
- Department of Hematology, Yokohama Minami-Kyousai Hospital
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- Tamai Hayato
- Division of Hematology and Oncology, Department of Internal Medicine, St. Marianna University School of Medicine
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- Nakayama Kazutaka
- Department of Hematology, Yokohama Minami-Kyousai Hospital
Bibliographic Information
- Other Title
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- pembrolizumab使用後に免疫性血小板減少症を発症した1例
- pembrolizumab シヨウ ゴ ニ メンエキセイ ケッショウバン ゲンショウショウ オ ハッショウ シタ 1レイ
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Description
<p>78歳，男性．再発肺腺癌に対し，pembrolizumab 3回投与で寛解を得たが，間質性肺炎の増悪のため，以降，治療は中止となった．約1年後，血小板数0.7万/μlまで低下，骨髄検査で巨核球の増加，異形成のないこと等から，免疫関連有害事象（immune-related adverse events：irAEs）としての免疫性血小板減少症（immune thrombocytopenia：ITP）と診断した．eltrombopagで治療を開始したところ，血小板数は速やかに正常化し，脾臓摘出後，現在無治療で良好な経過にある．</p>
Journal
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- Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi 110 (7), 1460-1466, 2021-07-10
The Japanese Society of Internal Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390292706102387456
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- NII Article ID
- 40022651962
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- NII Book ID
- AN00195836
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- ISSN
- 18832083
- 00215384
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- NDL BIB ID
- 031616144
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed