Cellular effects of chemically modified and mechanically defibrillated cellulose nanofibrils

DOI
  • FUJITA Katsuhide
    National Institute of Advanced Industrial Science and Technology
  • OBARA Sawae
    National Institute of Advanced Industrial Science and Technology
  • MARU Junko
    National Institute of Advanced Industrial Science and Technology
  • ENDOH Shigehisa
    National Institute of Advanced Industrial Science and Technology
  • MORIYAMA Akihiro
    National Institute of Advanced Industrial Science and Technology

Bibliographic Information

Other Title
  • 化学修飾および機械解繊セルロースナノファイバーの細胞影響

Abstract

<p>Cellulose nanofibrils (CNFs), also known as cellulose nanofibers, there is a concern about risks of inhalation toxicity. The cellular effects of two chemically modified CNFs and four mechanically defibrillated CNFs produced by different raw material species and manufacturing methods were investigated using rat alveolar macrophages (NR8383) and human airway epithelial cells (BEAS-2B) to study the cellular effects of CNFs. We believe that these results will be useful for predicting the human inhalation risk of CNFs and accelerate their industrial application. This study was supported by project grants from the New Energy and Industrial Technology Development Organization (NEDO).</p>

Journal

Details 詳細情報について

Report a problem

Back to top