A Case of Symplastic Glomus Tumor on the Pad of the Left First Toe

  • Kitada Hidenobu
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Kikuzawa Chiaki
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Bun Syota
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Deno Rikako
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Ikeda Aya
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Ozawa Kentaro
    Department of Dermatology, National Hospital Organization Osaka National Hospital
  • Kitamura Miwa
    Department of Dermatology, Kansai Medical University Temmabashi General Clinic

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Other Title
  • 左第 1 趾腹に生じた symplastic glomus tumor の 1 例

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Description

<p>A 74-year-old man presented with a painful nodule on the pad of the left first toe that had been present for 6 years. On examination, a reddish, elastic hard, mildly tender, mobile nodule (6×5 mm) was observed. Ultrasonography showed a hypoechoic mass without blood flow signal. These findings led to the suspicion of glomus tumor and the nodule was resected. Histopathological examination showed a well-defined nodular lesion that was composed of a sheet-like proliferation of round, eosinophilic cells with marked hyperchromatibility and variability in size and shape of nuclei. There was no increase in mitotic activities or atypical mitotic figures. In some cells, typical features of glomus tumor without nuclear atypia were observed. Immunohistochemistry revealed diffuse αSMA positivity and Ki-67 (mib-1)-positive cells were less than 1%. The tumor was diagnosed as symplastic glomus tumor, a variant of glomus tumor. Although it shows marked nuclear atypia and cellular variability, symplastic glomus tumor is a benign tumor that is clinically sharply marginated,superficially located, and small in size and histologically does not show increased mitotic activities or atypical mitotic figures. It is important to recognize this rare tumor and differentiate it properly from malignant tumor. Skin Research, 21 : 114-118, 2022 </p>

Journal

  • Hifu no kagaku

    Hifu no kagaku 21 (2), 114-118, 2022

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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