Organelle Metabolomics by Single-Cell Mass Spectrometry

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  • Mizuno Hajime
    Laboratory of Analytical Chemistry, Faculty of Pharmacy, Meijo University Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka
  • Yahata Kenji
    Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka
  • Sugiyama Eiji
    Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka
  • Todoroki Kenichiro
    Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka

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  • 1細胞質量分析による細胞内オルガネラメタボロミクス
  • 1 サイボウ シツリョウ ブンセキ ニ ヨル サイボウ ナイ オルガネラメタボロミクス

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Abstract

<p>Single-cell analysis is currently of interest to researchers in a wide range of fields, such as biology and medicine, and various methods of single-cell mass spectrometry have been developed. Molecular analysis focusing on intracellular regions such as organelle is expected to elucidate cellular functions in detail. Here, we introduce some metabolomics methods for single-cell organelle using high-sensitive mass spectrometry and their applications.</p>

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