Facial Allotransplantation －World Situation and Prospects－

DOI
  • OGAWA Rei
    Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School

Bibliographic Information

Other Title
  • 同種顔面移植手術 ～世界の現況と展望～

Description

<p>　　The world's first facial allotransplantation was performed in France in November 2005. Between 2005 and March 2022, 47 cases of surgery were performed. Currently, whole face transplantation is performed, in which soft tissue and facial bone are transplanted simultaneously. Facial allotransplantation surgery has emerged as a new technique for reconstruction of severe facial injuries that are limited by conventional free flaps, local flaps, and skin grafts. However, recipients need to take lifelong immunosuppressive drugs, and cases that die younger than the average life expectancy are increasing. In addition, the number of patients who receive a second face transplant is increasing because the face that was transplanted was rejected by an immune response. In this paper, we discuss the present situation based on the literature and reports from overseas media. Currently, the surgical procedure of allogeneic face transplantation has become established; however, it is essential to improve financial problems, patient’s mental care, and long-term maintenance of transplanted tissue for the future development of facial allotransplantation</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390293556142248832
  • DOI
    10.32154/jjscmfs.38.3_80
  • ISSN
    24337838
    0914594X
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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