Successful Total Management of Multi-Causative Sleep-Disordered Breathing Complicated with Patient with Adult Congenital Heart Disease

  • Suenaga Tomoyasu
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University
  • Ishikita Ayako
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University
  • Sakamoto Ichiro
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University
  • Nishizaka Mari
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University Department of Cardiovascular Medicine, Yagi Kouseikai, Yagi Hospital
  • Nishizaki Akiko
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University
  • Umemoto Shintaro
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University
  • Nagata Hazumu
    Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University
  • Yamamura Kenichiro
    Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University
  • Sonoda Hiromichi
    Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kyushu University
  • Yoshida Hiroko
    Sleep Apnea Center, Kyushu University Hospital
  • Ando Shin-Ichi
    Sleep Apnea Center, Kyushu University Hospital
  • Shiose Akira
    Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kyushu University
  • Tsutsui Hiroyuki
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University

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<p>Sleep-disordered breathing is one of the complications commonly seen in patients with adult congenital heart disease (ACHD) due to multiple causes including complex underlying cardiac defects, cardiomegaly, previous thoracotomies, obesity, scoliosis, and paralysis of the diaphragm. It is often hard to determine its main cause and predict the efficacy of each treatment in its management. We herein report a 30-year-old woman after biventricular repair of pulmonary atresia with intact ventricular septum diagnosed as sleep-related hypoventilation disorder. Simultaneous treatment targeting obesity, paralysis of the diaphragm, and cardiomegaly followed by respiratory muscle reinforcement through non-invasive ventilation resolved her sleep-related hypoventilation disorder. Such management for each factor responsible for the hypoventilation is expected to provide synergetic therapeutic efficacy and increase daily activity in a patient with ACHD.</p>

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