Diagnostic accuracy of synthesized two-dimensional mammography

DOI Web Site 15 References
  • Furuya Yuko
    Breast & Imaging Center St. Marianna University School of Medicine
  • Goto Yuka
    Breast & Imaging Center St. Marianna University School of Medicine
  • Tsugawa Koichiro
    Division of Breast Endocrine Surgery, Department of Surgery, St. Marianna University School of Medicine
  • Maezato Miwako
    Imaging Center of St. Marianna University School of Medicine
  • Fukuda Mamoru
    Breast & Imaging Center St. Marianna University School of Medicine

Bibliographic Information

Other Title
  • 合成２Ｄマンモグラフィの診断能の検証
  • versus Full-Field Digital Mammography
  • ―Full-Field Digital Mammography との比較―

Abstract

We conducted retrospective observational study in Japanese women to compare the diagnostic performance and characteristics between full-field digital mammography (FFDM) and synthesized two-dimensional mammography (s2D). The participants were 100 women (malignant: 43 cases; normal or benign: 57 cases) who underwent mammography for diagnostic/opportunistic screening at our institution between January 2017 and April 2018. The mean diagnostic sensitivity (by 6 observers) of s2D (72.1%) was higher than that of FFDM (62.0%). The mean specificity was almost equivalent, at 78.0% and 77.8%, respectively. There was no statistically significant difference of the mean figure of merit (FOM) between FFDM (0.637) and s2D (0.693)(p = 0.107).The mean sensitivity determined for each of the imaging findings revealed a significant difference only for architecture distortion, and there were category discordances between FFDM and s2D for all the findings. In Japanese women, s2D showed equal or better diagnostic performance than FFDM. Therefore, abbreviating FFDM and replacing s2D should be considered, because of the higher radiation dose exposure when digital breast tomosynthesis is applied. In addition, it is important to understand the differences in the characteristic imaging findings between FFDM and s2D.

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