Numerical Investigation of Fine particle Transportation and Deposition in the Human Lower Airway: Impact of airflow and particle size on deposition efficiency

DOI IR (HANDLE) Open Access
  • Nguyen Dang Khoa
    Interdisciplinary Graduate School of Engineering Sciences, Kyushu University
  • Nguyen Lu Phuong
    University of Natural Resources and Environment, Ho Chi Minh City
  • Ito Kazuhide
    Interdisciplinary Graduate School of Engineering Sciences, Kyushu University

Description

Understanding the deposition of inhaled toxic particles is critical in evaluating numerous health risks, especially in the lower airway. Recently, the computational fluid dynamics (CFD) method has been introduced as a promising method to facilitate the accurate prediction of airflow and particle behavior in complex geometry. Therefore, this study applied the CFD method to investigate the deposition characteristic of fine particles in the human respiratory tract from the nostrils to the 7th generation. The airflow pattern was simulated using the Eulerian method at breathing flow rates of 7.5 and 30 L/min, and was followed by particle (aerodynamic diameter 1 to 10μm) deposition simulation using the Lagrangian method. In general, the results were comparable with experimental data. The high deposited concentration of particles was found at the 5-7th generation, and a specific deposition hot-spot was observed at the carina ridge.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390294407618455936
  • DOI
    10.5109/5909118
  • HANDLE
    2324/5909118
  • ISSN
    24341436
  • Text Lang
    en
  • Data Source
    • JaLC
    • IRDB
    • Crossref
  • Abstract License Flag
    Allowed

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