A study of patients undergoing conchotome muscle biopsy for the diagnosis of polymyositis or dermatomyositis and its clinical usefulness

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  • 当科における多発性筋炎及び皮膚筋炎診断のためのコンコトーム筋生検施行症例とその有用性の検討

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Abstract

<p>Conchotome muscle biopsy is a type of muscle biopsy performed with cup forceps. Compared to open muscle biopsy, it has the advantages of being easier, less invasive, and safer, but its disadvantage is that the specimens obtained are smaller, which raises concerns about diagnostic accuracy. In our division, one of the authors, a rheumatologist, has performed conchotome muscle biopsy in a total of 7 cases of suspected polymyositis, dermatomyositis, and myositis as a partial manifestation of the disease since May 2019. All patients underwent MRI of both thighs prior to the examination, and the decision to biopsy from either the left or right vastus lateralis was based on the MRI findings. Pathological findings supporting the clinical diagnosis were obtained in 6 of the 7 patients. In all cases, no examination-related complications or postoperative complications occurred, and pain was mild. Traditionally, open muscle biopsy has been used for the pathological diagnosis of muscle diseases, but it requires special skill and only a limited number of medical institutions are able to perform it. In the pathological diagnosis of polymyositis and dermatomyositis, the diagnostic accuracy of conchotome muscle biopsy is not significantly inferior to that of open muscle biopsy, and it is sufficiently practical in situations where rapid diagnosis and treatment are needed with limited medical resources.</p>

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