Outcome of Low-Dose-Rate Brachytherapy in Patients with Prostate Cancer and the Characteristics of Patients with Recurrence
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- SAKATOKU Naoaki
- The Department of Urology, Kanazawa Medical Center
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- MIWA Sotaro
- The Department of Urology, Kanazawa Medical Center
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- SATO Ryo
- The Department of Urology, Kanazawa Medical Center
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- KOSHIDA Kiyoshi
- The Department of Urology, Kanazawa Medical Center
Bibliographic Information
- Other Title
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- 前立腺癌に対する密封小線源治療成績と再発症例の検討
- ゼンリツセン ガン ニ タイスル ミップウ ショウセン ゲン チリョウ セイセキ ト サイハツ ショウレイ ノ ケントウ
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Abstract
In our hospital, 553 patients with clinically localized prostate cancer underwent low-dose-rate (LDR) brachytherapy between March 2007 and December 2019. The patients were stratified based on the following prognosis according to the D'Amico risk classification criteria: low-risk and intermediate-risk groups (PSA <10, ≦T2a, GS : 3+4 (≦30%)) were treated with LDR brachytherapy without supplemental extra beam radiotherapy (EBRT), while some patients in the high- and intermediate-risk groups were treated with LDR and supplemental EBRT. The 5- and 10-year overall survival rates were 94.8 and 85.5%, disease-specific survival rates were 99.8 and 97.7%, and biochemical recurrence-free survival rates were 95.7 and 90.7%. By risk stratification, the 5- and 10-year biochemical recurrence-free survival rates were 98.0 and 98.0% (low risk), 96.1 and 89.6% (intermediate risk), and 90.6 and 77.3% (high risk). The LDR outcome was generally good, but, 32 recurrence cases were observed. In the recurrent group, 9 patients did not undergo the recommended therapeutic strategy and 26 patients did not undergo preoperative magnetic resonance imaging.
Journal
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- 泌尿器科紀要
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泌尿器科紀要 69 (1), 1-6, 2023-01-31
泌尿器科紀要刊行会
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Keywords
Details 詳細情報について
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- CRID
- 1390295027679400960
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- NII Book ID
- AN00208315
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- HANDLE
- 2433/279049
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- NDL BIB ID
- 032623425
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- ISSN
- 00181994
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
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- Abstract License Flag
- Allowed