Assessment of Airway Obstruction Using a Novel Multiple Pulmonary Function Measurement System (FB-8010<sup>®</sup>)
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- Nishine Hiroki
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Hiramoto Takehiko
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Matsuzawa Shin
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Kida Hirotaka
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Handa Hiroshi
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Maruta Katsuhiro
- COSMOSWEB Co., Ltd.,
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- Inoue Takeo
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
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- Miyazawa Teruomi
- Miyazawa Respiratory Clinic
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- Mineshita Masamichi
- Division of Respiratory Medicine, Department of Internal Medicine, St. Marianna University School of Medicine
Bibliographic Information
- Other Title
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- マルチ呼吸機能測定装置(FB-8010<sup>Ⓡ</sup>)を用いた気道狭窄の評価
Abstract
<p>Background. In severe airway obstruction, patients complain of dyspnea due to flow limitation, and respiratory failure can occur due to ventilation-perfusion mismatch. We previously reported the significance of estimating the regional pulmonary function during interventional bronchoscopy. The multiple pulmonary function measurement system (FB-8010®) has been certified in Japan since January 2020. Purpose. To assess the flow limitation and ventilation-perfusion mismatch in patients with airway obstruction using the multiple pulmonary function measurement system during bronchoscopy. Methods. Lateral airway pressure was measured simultaneously at two points using a double-lumen catheter and the pressure difference between two points was calculated. Lateral airway pressure was plotted on the x/y axes, representing the pressure-pressure curve (P-P curve). We then calculated the angle of the P-P curve defined as the angle between the peak inspiratory and expiratory pressure points and baseline of the angle. In addition, partial pressure of oxygen (PO2) and partial pressure of carbon dioxide (PCO2) were measured at the target region using a single-lumen catheter. Results. Pressure differences were noted at the site of airway obstruction, and the angle of the P-P curve was small. When flow limitation was restored after stenting, the pressure differences disappeared, and the angle of the P-P curve was closer to 45°. The baseline PO2 was lower for the severe bronchial obstruction side than the healthy side, and there was no marked difference in PCO2. After the airway was restored, the difference between the right and left was reduced in the baseline PO2. Conclusion. This novel multiple pulmonary function measurement system was able to assess the regional pulmonary function during bronchoscopy. The lateral airway pressure, PO2 and PCO2 help clarify the pathophysiology and estimate the outcome of interventional procedures in real-time.</p>
Journal
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- The Journal of the Japan Society for Respiratory Endoscopy
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The Journal of the Japan Society for Respiratory Endoscopy 45 (2), 82-88, 2023-03-25
The Japan Society for Respiratory Endoscopy
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Keywords
Details 詳細情報について
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- CRID
- 1390295603315233280
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- ISSN
- 21860149
- 02872137
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed