Longitudinal changes in the prevalence of adult asthma: An epidemiological survey among Japanese salaried employees and their dependents using healthcare insurance claim from 1999 to 2019

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  • Nagayama Kisako
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital
  • Fukutomi Yuma
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital
  • Nakatani Eiji
    Graduate School of Public Health, Shizuoka Graduate University of Public Health
  • Hamada Yuto
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital
  • Irie Mari
    Nihon Medical Insurance Institute Ltd.
  • Azekawa Kazuhiro
    MHI Co., Ltd.
  • Tomita Yasuhiro
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital Department of Respiratory Medicine, Anjo Kosei Hospital
  • Watai Kentaro
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital Shonan Kamakura General Hospital Center for Immunology and Allergology
  • Kamide Yosuke
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital
  • Sekiya Kiyoshi
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital
  • Nakamura Yoichi
    Medical Center for Allergic and Immune Diseases, Yokohama City Minato Red Cross Hospital
  • Okada Chiharu
    Headquarters, National Hospital Organization
  • Shimoda Terufumi
    Department of Allergy, National Hospital Organization Fukuoka National Hospital
  • Nagao Mizuho
    Allergy Center, National Hospital Organization Mie National Hospital
  • Fujisawa Takao
    Allergy Center, National Hospital Organization Mie National Hospital
  • Taniguchi Masami
    Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital Shonan Kamakura General Hospital Center for Immunology and Allergology

抄録

<p>Background: Information on changes in asthma prevalence and the treatment status for asthma is used as basic information for taking medical and administrative measures against asthma. However, this information among adults is relatively limited.</p><p>Methods: To elucidate changes in the prevalence of asthma and treatment status over time among Japanese adults, health insurance claim data from some health insurance societies covering salaried employees and their dependents were studied longitudinally. Claim data from FY1999 to 2007 were obtained from two health insurance societies, and data from FY 2011 to 2019 were obtained from three different health insurance societies, and changes in standardized asthma prevalence among subjects aged 20-59 years, proportion of asthma patients prescribed ICS, leukotriene receptor antagonist (LTRA), and LABA, and the mean number of acute asthma exacerbations per year were analyzed.</p><p>Results: The prevalence of asthma increased from 1.6% in 1999 to 3.0% in 2007 and 2.9% in 2011 to 4.6% in 2019. Increased trends in asthma prevalence from 2011 to 2019 were more noticeable in subjects in their 50s than those in their 20s for both sexes. The number of emergency visits related to asthma was 1.5 per year in 1999, which decreased to 0.8 per year in 2019. The proportion of people prescribed all anti-asthma medications (ICS, LTRA, and LABA) increased over time.</p><p>Conclusions: The prevalence of adult asthma among Japanese salaried employees and their dependents has increased over the last 20 years, suggesting more attention should be paid to the prevention of this disease in adults.</p>

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