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A CASE OF RECTAL INVASION BY NEUROENDOCRINE DIFFERENTIATED PROSTATE CANCER FORMING A LARGE SUBMUCOSAL TUMOR IN THE RECTUM
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- MIZUE Ryutaro
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University.
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- IHARA Yutaro
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University.
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- TORISU Takehiro
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University.
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- KAWATOKO Shinichiro
- Department of Anatomic Pathology, Pathological sciences, Graduate School of Medical Sciences, Kyushu University.
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- FUJIWARA Minako
- Department of Pathology, National Hospital Organization Kyushu Medical Center.
Bibliographic Information
- Other Title
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- 神経内分泌分化した前立腺癌による直腸転移の1例
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Description
<p>A 72-year-old man was diagnosed with prostate cancer 4 years ago and underwent heavy particle and hormone therapies at another hospital. A contrast-enhanced computed tomography (CT) scan, performed because of elevated hepatobiliary enzymes, did not show any abnormalities in the prostate. It did, however, show multiple hepatic masses, a mass shadow in the rectum, and enlarged surrounding lymph nodes. CS revealed a 40 mm submucosal tumor in the rectum with a depression in the apex. The tumor was biopsied and diagnosed as endocrine cell carcinoma. Chemotherapy initiation reduced the tumor size; however, a genomic analysis using a gene panel revealed the presence of prostate cancer-specific fusion gene TMPRSS2-ERG. This report describes a rare case in which neuroendocrine differentiation of prostate cancer was seen after hormone therapy, and the metastatic lesion grew rapidly and invaded the rectum.</p>
Journal
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- GASTROENTEROLOGICAL ENDOSCOPY
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GASTROENTEROLOGICAL ENDOSCOPY 65 (4), 353-360, 2023
Japan Gastroenterological Endoscopy Society
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Details 詳細情報について
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- CRID
- 1390295823371007232
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- ISSN
- 18845738
- 03871207
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed