An autopsy case of HHV8 negative common effusion lymphoma that developed during treatment for lung carcinoma
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- SHIMIZU Kaori
- Department of Pathology, Tokyo Teishin Hospital
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- HOSONE Masaru
- LSI Medience Corporation, Pathology/Cytology Laboratory Department of Integrated Diagnostic Pathology, Nippon Medical School
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- NAKAMURA Keiko
- Department of Pathology, Tokyo Teishin Hospital
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- TAKAHASHI Takeshi
- Department of Pathology, Tokyo Teishin Hospital
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- TAJIRI Ryosuke
- Department of Pathology, Tokyo Teishin Hospital
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- TAMURA Koichi
- Department of Pathology, Tokyo Teishin Hospital
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- KISHIDA Yukiko
- Department of Pathology, Tokyo Teishin Hospital
Bibliographic Information
- Other Title
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- 肺癌治療中に発症した HHV8-negative common effusion lymphoma の 1 剖検例
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Abstract
<p>Background : HHV8-negative common effusion lymphoma (HENCEL) is a type of malignant lymphoma arising in body cavities that differs both clinically and histopathologically from primary effusion lymphoma (PEL) ; their differential diagnosis is crucial in cytology specimens.</p><p>Case : A man in his 80s who was undergoing treatment for pulmonary adenocarcinoma presented with left pleural effusion. HENCEL was diagnosed by systemic examination and cytology. The tumor cells were smaller in size in the liquid-based cytology (LBC) specimen than in the conventional smear cytology, however, three-dimensional observation revealed irregularity of the nuclear membrane, which led to the diagnosis. The diagnosis of HENCEL combined with lung adenocarcinoma was confirmed at autopsy.</p><p>Conclusion : If cells suspected as belonging to malignant lymphoma are found in the pleural effusion, it is important to rule out secondary involvement of systemic lymphoma as well as PEL, when considering the possibility of HENCEL. Combined use of LBC with smear cytology can provide useful information for the diagnosis and contribute to improvement of the diagnostic accuracy of HENCEL.</p>
Journal
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- The Journal of the Japanese Society of Clinical Cytology
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The Journal of the Japanese Society of Clinical Cytology 62 (2), 98-104, 2023
The Japanese Society of Clinical Cytology
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Keywords
Details 詳細情報について
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- CRID
- 1390296033830539904
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- ISSN
- 18827233
- 03871193
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed