Oclacitinib as a therapeutic proposal in feline pemphigus foliaceus

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  • Nosach Nancy Raquel
    Department of Clinical Pathology and Medical Diseases, School of Veterinary Medicine, Buenos Aires University Dermatology Service, School of Veterinary Medicine, Buenos Aires University
  • Blanco Alejandro Diego
    Dermatology Service, School of Veterinary Medicine, Buenos Aires University
  • Duarte Marcelo José
    Dermatology Service, School of Veterinary Medicine, Buenos Aires University

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  • オクラシチニブを用いた猫の落葉状天疱瘡の治療案

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Abstract

<p>Pemphigus foliaceus is an immune-mediated disease characterized by the formation of autoantibodies directed against epidermal intercellular junctions. Conventional treatments include the administration of immunosuppressive doses of glucocorticoids. The objective of this work is to present a cat with a histopathological diagnosis of pemphigus foliaceus that, due to its pre-existing cardiac pathology, was treated with oclacitinib (Apoquel®, Zoetis, Buenos Aires, Argentina), a Janus kinase (JAK) inhibitor in order to avoid long-term side effects of oral corticosteroids.</p>

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