Prenatal diagnosis and management of large oral tumor originating from the brain: a case report

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  • AKASAKA Oriha
    Department of Obstetrics and Gynecology, Nara Medical University
  • Ryuta MIYAKE
    Department of Obstetrics and Gynecology, Nara Medical University
  • OKAMOTO Miho
    Department of Obstetrics and Gynecology, Nara Medical University
  • ONISHI Shunsuke
    Department of Obstetrics and Gynecology, Nara Medical University
  • ICHIKAWA Mayuko
    Department of Obstetrics and Gynecology, Nara Medical University
  • NARUSE Katsuhiko
    Department of Obstetrics and Gynecology, Nara Medical University
  • KIMURA Fuminori
    Department of Obstetrics and Gynecology, Nara Medical University
  • AKASAKA Juria
    Department of Obstetrics and Gynecology, Nara Medical University

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Other Title
  • 胎児期に発見され致死的な気道閉塞をきたした脳組織由来の巨大口腔内腫瘤の1例
  • タイジキ ニ ハッケン サレ チシテキ ナ キドウ ヘイソク オ キタシタ ノウ ソシキ ユライ ノ キョダイグチ コウナイ シュリュウ ノ 1レイ

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Abstract

In the present case, an epignathus was suspected in one of a pair of dichorionic diamniotic twins at 22 weeks of gestation. The tumor grew bigger and became complicated with polyhydramnios from 30 weeks of gestation. By the case conference held by obstetrics, anesthesiologist, neonatologist and pediatric surgeon, elective cesarean section was performed at 34 weeks of gestation. Despite the intensive treatment, the baby died due to airway management difficulty. The histopathological findings of the mass was met for encephalocele rather than epignathus. There are many reports that if the big mass in front of the mouth that obstruct airway is removed, it might not interfere with the subsequent neonatal growth and development. However, as in this case, the tumor may be suspected as an encephalocele by a histopathological examination, and the neurologic prognosis of the newborn may be poor even if surgically desected. [Adv Obstet Gynecol, 75(3) : 249-254, 2023 (R5.8)]

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