Dysesthesia-matched transcutaneous electrical nerve stimulation cancels out the dysesthesias by central nervous disorders: single-case experimental design

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  • NISHI Yuki
    Institute of Biomedical Sciences (Health Sciences), Nagasaki University Neurorehabilitation Research Center, Kio University
  • IKUNO Koki
    Department of Rehabilitation Medicine, Nishiyamato Rehabilitation Hospital
  • MINAMIKAWA Yuji
    Department of Rehabilitation Medicine, Nishiyamato Rehabilitation Hospital
  • NAKATA Keisuke
    Department of Rehabilitation Medicine, Nishiyamato Rehabilitation Hospital
  • OSUMI Michihiro
    Neurorehabilitation Research Center, Kio University
  • MORIOKA Shu
    Neurorehabilitation Research Center, Kio University

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  • 中枢神経障害によるしびれ感に対するしびれ同調経皮的電気神経刺激の効果検証：シングルケース実験デザイン

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<p>Our previous study revealed that the dysesthesia-matched TENS (DM-TENS) effects for dysesthesias in patients with central nervous system dysfunctions. A total of 8 upper extremity sites with dysesthesias in 5 patients (2 stroke patients, 2 spinal cord injury patients, and 1 multiple sclerosis patient) were included in the study. Multiple-baseline design set with a baseline phase, intervention phase, and follow-up phase of total 28 days. In the intervention phase for 7 days, DM-TENS was applied to upper extremity sites with dysesthesias at 1 hour per day. Patients answered the numerical rating scale for the intensities of subjective dysesthesias every day. The Between-case standardized mean difference (BC-SMD) for the between-case effects and Tau-U for the within-case effects were calculated. In the results of BC-SMD, the dysesthesias were significantly improved by DM-TENS in the intervention and follow-up phases. Moreover, within-case effects were high in all patients during the intervention phase. However, both hands of one spinal cord injury patient did not show significant improvement during the follow-up phase, despite the similar severities of the spinal cord injury and dysesthesias to another patient. Our results suggest the effectiveness of DM-TENS for the dysesthesias caused by central neuropathies. Additional investigation of the factors involved in the intervention effect is needed.</p>

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