OPAT is an Effective Treatment in a CRBSI Patient With Hypoganglionosis: Report of a Case

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  • 外来抗菌薬静注療法が有用であったヒルシュスプルング病類縁疾患の患児に発症した中心静脈カテーテル関連血流感染症の1例
  • ガイライ コウキンヤク ジョウチュウ リョウホウ ガ ユウヨウ デ アッタ ヒルシュスプルングビョウ ルイエン シッカン ノ カンジ ニ ハッショウ シタ チュウシン ジョウミャク カテーテル カンレン ケツ リュウカンゾメショウ ノ 1レイ

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Abstract

<p>A boy aged one year and 11 months, who presented with hypoganglionosis and was given parenteral nutrition at home, required prophylactic ethanol lock therapy (pELT) as a regular outpatient because he had recurrent catheter-related bloodstream infection (CRBSI). Four days before his admission, he had no symptoms and a central venous catheter joint wipe culture was carried out. One day before his admission, he had a high fever. He was subjected to outpatient parenteral antimicrobial therapy (OPAT) using ceftriaxone (CTRX) and ELT because Klebsiella was detected in the wipe culture and his treatment was difficult in his home environment. He was intravenously given CTRX at 60 mg/kg body weight and ELT for two hours so that he could be healed in 10 days. When the condition of the patient is stable and the antimicrobial drug to be used is determined, OPAT in a CRBSI patient can become one of the management options.</p>

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