Effect of Iron and/or Zinc Deficiency in Rats

  • Konomi Aki
    Department of Human Nutrition, Seitoku University Graduate School
  • Yokoi Katsuhiko
    Department of Human Nutrition, Seitoku University Graduate School

Bibliographic Information

Other Title
  • 鉄・亜鉛の単独および同時欠乏が生体に及ぼす影響

Search this article

Description

<p>Iron (Fe) and zinc (Zn) are suspected to be easily depleted in humans at the same time, because dietary sources such as meat and major absorption inhibitors such as calcium and phytate are common for Fe and Zn. To determine the effects of Fe and/or Zn deficiencies on physiological parameters in rats, forty 4-week-old male Sprague-Dawley rats were assigned into 4 dietary treatment groups: severely Fe-deficient (FD), moderately Zn-deficient (ZD), severely Fe-deficient/moderately Zn-deficient (FZD), and control (Cont). Body temperature of FD and ZD were decreased, but that of FZD was not changed. TIBC was decreased by Fe deficiency. Hemoglobin and hematocrit were decreased by Fe deficiency and increased by Zn deficiency. Total body water per body weight was increased in FZD and intracellular water/extracellular water ratio was increased in ZD. Plasma erythropoietin concentration was markedly decreased by Zn deficiency.</p>

Journal

Details 詳細情報について

  • CRID
    1390297924422124288
  • DOI
    10.51029/jtnrs.24.0_82
  • ISSN
    24366617
    13462334
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Allowed

Report a problem

Back to top