Pathological diagnosis of pancreatic neuroendocrine neoplasm (NEN)

DOI Web Site 9 References
  • OHIKE Nobuyuki
    Division of Molecular Pathology, Department of Pathology, St. Marianna University School of Medicine Division of Pathology, Shizuoka Cancer Center
  • NOROSE Tomoko
    Division of Molecular Pathology, Department of Pathology, St. Marianna University School of Medicine Division of Pathology, Shizuoka Cancer Center
  • SUGIURA Yoshiya
    Division of Molecular Pathology, Department of Pathology, St. Marianna University School of Medicine
  • TAKATSUKI Misato
    Division of Molecular Pathology, Department of Pathology, St. Marianna University School of Medicine
  • KOIZUMI Hirotaka
    Division of Molecular Pathology, Department of Pathology, St. Marianna University School of Medicine
  • SUGINO Takashi
    Division of Pathology, Shizuoka Cancer Center
  • KOIKE Junki
    Department of Pathology, St. Marianna University School of Medicine

Bibliographic Information

Other Title
  • 膵神経内分泌腫瘍（NEN）の病理診断

Abstract

<p>In pancreatic neuroendocrine neoplasms (NENs) classification, neuroendocrine tumors (NET G1-3) and neuroendocrine carcinomas (NEC) appear to be on the same spectrum, but their histogenesis and molecular biological behavior are radically different, which affects treatment strategies. Therefore, it is necessary to recognize them as completely different pathological entities and conduct appropriate pathological diagnoses. For cases when differential diagnosis is difficult using ordinary diagnostic methods, it is desirable that the pathologist establishes a communicative relationship with clinicians that allows for consideration of pathological, clinical prognostic, and treatment-related factors.</p>

Journal

  • Suizo

    Suizo 38 (6), 381-389, 2023-12-28

    Japan Pancreas Society

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