Diagnosis and therapy of pancreatic NEN using peptide receptor radioligands

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  • HOSONO Makoto
    Department of Radiology, Kindai University Faculty of Medicine

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  • ペプチド受容体放射性リガンドを用いた膵NENの診断と治療

Abstract

<p>Radiopharmaceuticals consisting of radionuclides and somatostatin analogues for imaging and therapy are essential for theranostics. As imaging plays a major role in managing pancreatic and other neuroendocrine neoplasms (NEN), somatostatin receptor imaging and peptide receptor radionuclide therapy (PRRT) using somatostatin analogues with high tumor affinity has become indispensable for treatment. PRRT is safe, effective and can be used to treat NEN in any primary organ. Currently, it is positioned as a second-line treatment or later, but further studies can investigate its use as a first-line treatment and beyond four-dose protocols.</p>

Journal

  • Suizo

    Suizo 38 (6), 375-380, 2023-12-28

    Japan Pancreas Society

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