Neural Circuits for Saccade Initiation and Fixation

DOI
  • Takahashi Mayu
    Department of Systems Neurophysiology, Tokyo Medical and Dental University

Bibliographic Information

Other Title
  • サッケードのトリガー神経回路と固視の神経回路

Abstract

<p>　Omnipause neurons (OPNs) in the nucleus raphe interpositus in the brainstem have tonic ac tivity while our eyes fixate but stop firing before and during saccades. We analyzed synaptic in puts from the rostral and caudal superior colliculi (SCs) to OPNs. The intracellular recording and staining techniques were used to identify the neural substrate for inhibiting OPNs for saccade initiation. OPNs received excitation from the rostral SC and inhibition from the caudal SC. Fur thermore, we demonstrated that the inhibition from the SC to OPNs was mediated by inhibitory burst neurons (IBNs) by sectioning the midline between the bilateral IBNs. These results indicat ed that there is no special supranuclear signal for triggering saccades, but instead, the signal for inhibiting OPNs comes from IBNs of saccadic driving pathways.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390298742738480896
  • DOI
    10.11476/shinkeiganka.40.390
  • ISSN
    21882002
    02897024
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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