NATIONWIDE SURVEY ON HEMATOPOIETIC STEM CELL HARVEST AND OTHER APHERESIS IN JAPAN

  • Yakushijin Kimikazu
    Department of Medical Oncology and Hematology, Kobe University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Yoshihara Satoshi
    Department of Hematology, Hyogo Medical University Hospital Department of Transfusion and Cellular Therapy, Hyogo Medical University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Ikemoto Junko
    Department of Transfusion and Cellular Therapy, Hyogo Medical University Hospital
  • Ikeda Kazuhiko
    Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Ishida Akaru
    Division of Transfusion Medicine and Cell Transplantation, Saitama Medical University International Medical Center Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Ohto Hitoshi
    Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Ohara Akira
    Toho University Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Kajiwara Michiko
    Center for Transfusion Medicine and Cell Therapy, Tokyo Medical and Dental University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Kikuta Atsushi
    Department of Pediatric Oncology, Fukushima Medical University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Haraguchi Kyoko
    Division of Transfusion and Cell Therapy, Tokyo Metropolitan Komagome Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Fujiwara Shin-ichiro
    Division of Cell Transplantation and Transfusion, Jichi Medical University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Yamada-Fujiwara Minami
    Division of Blood Transfusion and Cell Therapy, Tohoku University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Yamazaki Rie
    Center for Transfusion Medicine and Cell Therapy, Keio University School of Medicine Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Nagamura-Inoue Tokiko
    Department of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Tanosaki Ryuji
    Center for Transfusion Medicine and Cell Therapy, Keio University School of Medicine Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Okuyama Yoshiki
    Division of Transfusion and Cell Therapy, Tokyo Metropolitan Komagome Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Fujimori Yoshihiro
    Department of Transfusion and Cellular Therapy, Hyogo Medical University Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy
  • Ueda Yasunori
    Department of Hematology/Oncology, Kurashiki Central Hospital Cytapheresis Working Group, The Japan Society of Transfusion Medicine and Cell Therapy

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Other Title
  • 本邦における造血幹細胞採取等のアフェレーシスの実態調査

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<p>Peripheral blood stem cell harvesting (PBSCH) is an established general practice; however, recent medical advances have led to diversification in hematopoietic stem cell transplantation and collection. A questionnaire survey on cell therapy and blood cell apheresis was conducted to understand the current situation and identify issues in Japan. A total of 159 facilities/departments responded to the survey. The annual number of autologous PBSCH was "11-25" in 48% and "1-10" in 37% of the centers, while the annual number of allogeneic PBSCH for related transplantation was "1-10" in 60% of the centers and "1-10" in 50% for unrelated transplantation. Collection sites were in the wards (40%), transfusion department (36%), and dialysis unit (26%). The apheresis system was staffed mainly by clinical engineers (67%) and doctors (23%). Primarily, doctors (96%) performed peripheral vascular punctures and were present at all times during collection in 37% of the centers. The Spectra Optia was the equipment most commonly used for apheresis. To freeze the product, 89% of the centers used "CP-1" without a controlled rate freezer. This survey revealed the diversification of collection methods in Japan, with "task shift" emerging as a significant concern.</p>

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