Effect of denture adhesives on masticatory performance: Multicenter randomized controlled trial

  • Kimoto Suguru
    The Japan Denture Care Society Department of Gerodontology and Home Care Dentistry, School of Dentistry Aichi Gakuin University, Nagoya, Japan
  • Kawai Yasuhiko
    The Japan Denture Care Society Department of Removable Prosthodontics and Geriatric Oral Health, Nihon University School of Dentistry at Matsudo, Matsudo, Japan
  • Suzuki Asako
    The Japan Denture Care Society Department of Removable Prosthodontics and Geriatric Oral Health, Nihon University School of Dentistry at Matsudo, Matsudo, Japan
  • Koide Yasuyo
    The Japan Denture Care Society Department of Removable Prosthodontics and Geriatric Oral Health, Nihon University School of Dentistry at Matsudo, Matsudo, Japan
  • Kondo Hisatomo
    The Japan Denture Care Society Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University, Morioka, Japan
  • Nomura Taro
    The Japan Denture Care Society Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University, Morioka, Japan
  • Tsuboi Akito
    The Japan Denture Care Society Division of Aging and Geriatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
  • Ito Yoshihiko
    The Japan Denture Care Society Division of Aging and Geriatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
  • Hong Guang
    The Japan Denture Care Society Division for Globalization Initiative, Liaison Center for Innovative Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
  • Minakuchi Shunsuke
    The Japan Denture Care Society Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Ohwada Gaku
    The Japan Denture Care Society Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Sato Yusuke
    The Japan Denture Care Society Gerodontology and Oral Rehabilitation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  • Suzuki Tetsuya
    The Japan Denture Care Society Section of Oral Prosthetic Engineering, Tokyo Medical and Dental University, Tokyo, Japan
  • Kimoto Katsuhiko
    The Japan Denture Care Society Department of Fixed Prosthodontics, Kanagawa Dental University, Yokosuka, Japan
  • Saita Makiko
    The Japan Denture Care Society Department of Fixed Prosthodontics, Kanagawa Dental University, Yokosuka, Japan
  • Hoshi Noriyuki
    The Japan Denture Care Society Department of Fixed Prosthodontics, Kanagawa Dental University, Yokosuka, Japan Department of Education Planning, Kanagawa Dental University, Yokosuka, Japan
  • Yoneyama Yoshikazu
    The Japan Denture Care Society Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan
  • Sato Yohei
    The Japan Denture Care Society Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan
  • Morokuma Masakazu
    The Japan Denture Care Society Morokuma Dental Clinic, Nagasaki, Japan
  • Okazaki Joji
    The Japan Denture Care Society Department of Removable Prosthodontics and Occlusion, Osaka Dental University, Hirakata, Japan
  • Maeda Takeshi
    The Japan Denture Care Society Department of Removable Prosthodontics and Occlusion, Osaka Dental University, Hirakata, Japan
  • Nakai Kenichiro
    The Japan Denture Care Society Department of Removable Prosthodontics and Occlusion, Osaka Dental University, Hirakata, Japan
  • Ichikawa Tetsuo
    The Japan Denture Care Society Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Nagao Kan
    The Japan Denture Care Society Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Fujimoto Keiko
    The Japan Denture Care Society Department of Prosthodontics and Oral Rehabilitation, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan
  • Kurogi Tadafumi
    The Japan Denture Care Society Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Murata Hiroshi
    The Japan Denture Care Society Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Okazaki Hitomi
    The Japan Denture Care Society Department of Prosthetic Dentistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
  • Nishimura Masahiro
    The Japan Denture Care Society Department of Oral and Maxillofacial Prosthodontics, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
  • Nishi Yasuhiro
    The Japan Denture Care Society Department of Oral and Maxillofacial Prosthodontics, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
  • Murakami Mamoru
    The Japan Denture Care Society Removable Prosthodontics and Implant Dentistry, Kagoshima University Hospital, Kagoshima, Japan
  • Hosoi Toshio
    The Japan Denture Care Society Tsurumi University School of Dental Medicine, Yokohama, Japan
  • Hamada Taizo
    The Japan Denture Care Society Hiroshima University, Hiroshima, Japan

抄録

<p>Purpose: The purpose of this study is to investigate the effects of denture adhesives on masticatory performance via a 10-center, parallel, randomized, controlled trial of complete denture wearers in Japan.</p><p>Methods: The trial was conducted between September 2013 and October 2016. The inclusion criteria were complete edentulism, willingness to undergo new complete denture treatment, and willingness to return for recall treatment. The exclusion criteria were age 90 years or older, presence of severe systemic illness, inability to understand the questionnaires, wearing metal base complete dentures, denture adhesive user, wearing prosthetics for maxillofacial defects, wearing complete dentures with tissue conditioners, and severe xerostomia. Randomization of the powder-type denture adhesive (powder), cream-type denture adhesive (cream), and control (saline) groups was performed using a sealed envelope system. Masticatory performance was measured using color-changeable chewing gum. Intervention blinding was not feasible. </p><p>Results: Sixty-seven control, 69 powder, and 64 cream participants are analyzed using the intention-to-treat principle. The participants in all groups show significantly improved masticatory performance at post-intervention (paired t-test with Bonferroni correction P < 0.0001). However, no significant difference in masticatory performance is detected among the three groups (one-way analysis of variance). A significant negative correlation between pre- and post-changes in masticatory performance and intraoral condition scores is observed (Pearson’s correlation coefficient, P < 0.0001).</p><p>Conclusions: Although denture adhesives improved the masticatory performance of complete denture wearers, their clinical effects are comparable to those of saline solution. The use of denture adhesives is more effective in complete denture wearers with unsatisfactory intraoral conditions.</p>

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