Use of Silkworms to Reveal the Functions of Intestinal Bacteria

DOI

Bibliographic Information

Other Title
  • 腸内細菌の機能を知るためのカイコの利用

Abstract

<p>An imbalance in the intestinal microbiota affects the onset and progression of various diseases, including infectious diseases, lifestyle-related diseases, and cancer. Therefore, understanding host–microbe interactions in the gut microbiota contributes to the development of the prevention and treatment of these diseases. Typically, antimicrobial-treated mice or gnotobiotic mice are used for research; however, there are costs and ethical issues involved. Here, we outline studies that have used silkworms as alternative animals. Silkworms can be used in experiments with a large number of individuals, especially because the ethical issues are small. Pathological models of infectious diseases and diabetes have been established using silkworms as the experimental animals. These pathological silkworm models are useful for the identification of lactic acid bacteria, which are expected to have preventive effects against infectious diseases and diabetes.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390299008194679936
  • DOI
    10.11209/jim.38.1
  • ISSN
    13498363
    13430882
  • Text Lang
    en
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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