Gut Microbiota Research using <i>C. elegans</i>

DOI
  • KAGE-NAKADAI Eriko
    Laboratory of Environment and Health Science, Graduate School of Human Life and Ecology, Osaka Metropolitan University

Bibliographic Information

Other Title
  • 線虫を利用した腸内細菌研究

Abstract

<p>Many approaches to disease and health control have been attempted using intestinal bacteria and probiotics. However, the molecular mechanisms of the interactions between intestinal bacteria and their hosts are still largely unknown. Caenorhabditis elegans (C. elegans) is one of the model organisms that have played an important role in discoveries which garnered three Nobel Prizes. Since the report of prolongevity effects of lactobacilli and bifidobacteria on Caenorhabditis elegans, together with moves to reduce or eliminate mammalian experiments, knowledge on the biological effects of probiotics and beneficial bacteria using Caenorhabditis elegans as an alternative model has been rapidly accumulating. Our understanding of the intestinal microbiota of the wild C. elegans has also progressed. The C. elegans model is expected to be intensively utilized to elucidate intestinal microbiota-host interactions.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390299008194684800
  • DOI
    10.11209/jim.38.9
  • ISSN
    13498363
    13430882
  • Text Lang
    en
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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