‟Innovation from Dentistry”

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  • Nikawa Hiroki
    Department of Oral Biology & Engineering, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Taji Tsuyoshi
    Department of Oral Biology & Engineering, Graduate School of Biomedical and Health Sciences, Hiroshima University

Bibliographic Information

Other Title
  • 歯科からのイノベーション
  • – The inside story of from research to patents, licenses and royalty income –
  • ─研究〜特許〜ライセンス〜ロイヤリティ収入の裏話─

Abstract

<p>For patients who cannot take care of their own oral cavity, the idea of controlling biofilms by using the factors involved in biofilm formation has led to industry-academia collaboration. There are two major researches, the first is the use of L8020 lactic acid bacteria. The oral cavity contains a resident microflora called oral flora. Similar to the intestinal flora, oral flora contain lactic acid bacteria, so we have been conducting research on the application of probiotics to the oral cavity. In particular, we introduce seeds using Lactobacillus rhamnosus (L8020 lactic acid bacterium), which exhibits high antibacterial effects against mutans streptococci, periodontalburdens, and Candida species.</p><p>Second, in order to add antibacterial properties to the surface of teeth and implants, we developed Etak, which has both an antiseptic part used for disinfecting skins and/or mucosa, and a silane-based immobilization part. The Etak makes it possible to easily antibacterially process things that have not had antibacterial properties so far just by spraying or immersing them. This Etak also has an antiviral effect and is used for various purposes.</p><p>In this paper, we would like to introduce specific examples of industry-university collaborative research, such as patent acquisition and royalties from L8020 and Etak.</p>

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