Recurrent Stroke with Rapid Development of Intracranial Artery Stenosis and Subsequent Successful Mechanical Thrombectomy in Essential Thrombocythemia
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- Kato Yuji
- Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Japan
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- Iijima Shohei
- Department of Endovascular Neurosurgery, Saitama Medical University International Medical Center, Japan
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- Kohyama Shinya
- Department of Endovascular Neurosurgery, Saitama Medical University International Medical Center, Japan
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- Maeda Tomoya
- Department of Hemato-Oncology, Saitama Medical University International Medical Center, Japan
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- Sato Tsugumi
- Department of Pathology, Saitama Medical University International Medical Center, Japan
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- Takahashi Shinichi
- Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Japan
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- Suda Satoshi
- Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Japan
抄録
<p>Essential thrombocythemia is a myeloproliferative neoplasm. Ischemic stroke is frequently the first manifestation of essential thrombocythemia. We herein report a patient with JAK2V617 mutation-positive essential thrombocythemia who developed recurrent ischemic stroke with rapid development of intracranial artery stenosis and subsequently underwent successful mechanical thrombectomy. The high JAK2V617F allele burden in our patient (58.4%) may have affected the patient's condition. We discuss similar reports in the literature and the possible pathophysiologic mechanism of large artery involvement in these patients. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 63 (6), 847-852, 2024-03-15
一般社団法人 日本内科学会