Experience of Rehabilitation Treatment for Osmotic Demyelination Syndrome with Locked-in Syndrome
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- Doi Akane
- Department of Rehabilitation Medicine, Osaka Medical and Pharmaceutical University
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- Tomioka Masao
- Department of Rehabilitation Medicine, Osaka Medical and Pharmaceutical University
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- Saura Ryuichi
- Department of Rehabilitation Medicine, Osaka Medical and Pharmaceutical University
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- Kimura Fumiharu
- Osaka Medical and Pharmaceutical University Mishima-minami Hospital
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- Ota Shin
- Osaka Medical and Pharmaceutical University Mishima-minami Hospital Department of Internal Medicine Ⅳ, Osaka Medical and Pharmaceutical University
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- Hosokawa Takafumi
- Department of Internal Medicine Ⅳ, Osaka Medical and Pharmaceutical University
Bibliographic Information
- Other Title
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- 閉じ込め症候群を呈した浸透圧性脱髄症候群に対するリハビリテーション治療の経験
Description
<p>Osmotic demyelination syndrome is a pathological condition that leads to electrolyte imbalances and rapid correction, resulting in pseudobulbar palsy, quadriplegia, and altered consciousness. Approximately 33-55% of affected patients experience residual functional impairment. Herein, we describe a case of a patient with osmotic demyelination syndrome who developed locked-in syndrome during the disease course, underwent rehabilitation treatment, and achieved complete remission without sequelae.</p><p>The patient was a 47-year-old man who was admitted to hospital A owing to weakness in the lower extremities and dysarthria. He had severe hyponatremia and received sodium correction. However, on hospital day 9, dysarthria redeveloped and involuntary finger movements were noted. Osmotic demyelination syndrome was suspected based on the findings of magnetic resonance imaging of the head and clinical course, leading to his transfer to hospital B. Steroid pulse and rehabilitation therapies were initiated at hospital B. By the 19th day of symptom onset, his limb and facial muscle paralysis progressed, leading to locked-in syndrome. Thereafter, the patient was transferred to hospital C, where he received physiotherapy, occupational therapy, and eating training, markedly improving his physical functions. He was discharged from hospital C, 4 months after the symptom onset, with limited range of motion of the fingers and weakness of the extremities and continued to receive outpatient rehabilitation treatment. His symptoms improved further, and 1 year after the onset of symptoms, he returned to work without any sequelae.</p>
Journal
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- The Japanese Journal of Rehabilitation Medicine
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The Japanese Journal of Rehabilitation Medicine advpub (0), 2024-03-18
The Japanese Association of Rehabilitation Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390299517765913728
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- ISSN
- 18818560
- 18813526
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed