A CASE OF GASTRIC NEUROENDOCRINE TUMOR IN A PATIENT WITH AUTOIMMUNE GASTRITIS COMPLICATED BY TYPE 3 AUTOIMMUNE POLYENDOCRINE SYNDROME TYPE 3

DOI IR Open Access
  • OKADA Yasuyuki
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • OKAMOTO Koichi
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • TANI Naoya
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • WADA Hironori
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • KAWAGUCHI Tomoyuki
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • NODA Kazuyoshi
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • MIYAMOTO Yoshihiko
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.
  • SHUNTO Joji
    Shunto Clinic.
  • UEHARA Hisanori
    Division of Pathology, Tokushima University Hospital.
  • TAKAYAMA Tetsuji
    Department of Gastroenterology and Oncology, Tokushima University Graduate School.

Bibliographic Information

Other Title
  • 胃神経内分泌腫瘍を合併した多腺性自己免疫症候群３型の１例

Search this article

Description

<p>A 66-year-old woman who developed type I diabetes mellitus at the age of 50 years was referred to our hospital because of gastric submucosal lesion in the stomach. EGD identified a submucosal lesion, approximately 5 mm in diameter, in the lesser curvature of the middle stomach and showed the corpus dominant atrophy and pseudopyloric metaplasia with the corpus posterior walls. She had positive serum anti-parietal cell and anti-intrinsic factor antibodies. Based on endoscopic findings and histological analysis, G1 gastric neuroendocrine tumor (NET) along with autoimmune gastritis was diagnosed. Additional serological analysis revealed chronic thyroiditis, leading to the final diagnosis of type 3 autoimmune polyendocrine syndrome (APS). ESD was performed for the gastric lesion. Histopathological evaluation revealed a G1 NET. This case suggests that gastroenterologists should be aware of APS and perform EGD for patients with slow progressive type I diabetes mellitus and autoimmune gastritis.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top