Biocompatibility of dental implants coated with hydroxyapatite using pulsed Er:YAG laser deposition
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- KUKI Yuri
- Department of Oral Implantology, School of Dentistry, Osaka Dental University
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- MORINAGA Kenzo
- Department of Oral Implantology, School of Dentistry, Osaka Dental University
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- UEMURA Naoya
- Department of Oral Implantology, School of Dentistry, Osaka Dental University
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- OKAMURA Tomoharu
- Department of Oral Pathology, School of Dentistry, Osaka Dental University
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- HONTSU Shigeki
- Department of Biomedical Engineering, Faculty of Biology-Oriented Science and Technology, Kindai University
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- HASHIMOTO Yoshiya
- Department of Biomaterials, School of Dentistry, Osaka Dental University
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- BABA Shunsuke
- Department of Oral Implantology, School of Dentistry, Osaka Dental University
抄録
<p>We aimed to improve the biocompatibility and osteoinductive potential of Ti implants using a simulated intraoral hydroxyapatite (HAp) coating. We devised a novel surface treatment for aggressive induction of osteoblast adhesion and bone regeneration on the implant surface. A thin α-tricalcium phosphate (α-TCP) film was deposited on the implant surface using a pulsed Er:YAG laser. The coating was converted to HAp through artificial saliva immersion, which was confirmed using scanning electron microscopy (SEM) and X-ray diffraction (XRD). SEM showed needle-like HAp crystals on the Ti disks and sandblasted implant surfaces after immersion in artificial saliva for 96 h. Microcomputed tomography and histological evaluation 4 and 8 weeks after implantation into beagle dog mandibles showed that the HAp-coated implant was biocompatible and exhibited superior osteoinduction compared to that of sandblasted implants. Coating the implant surface with HAp using an Er:YAG laser has potential as a new method of the implant-surface debridement.</p>
収録刊行物
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- Dental Materials Journal
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Dental Materials Journal 43 (2), 269-275, 2024-03-25
一般社団法人 日本歯科理工学会