Pseudomesotheliomatous Carcinoma of the Lung with Morphological Characteristics of Signet Ring Cell Carcinoma: An Autopsy Case Report

  • Hirakawa Tetsu
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Tanimoto Takuya
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Hattori Yui
    Department of Pathology and Laboratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Katsura Ryo
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Miyake Shinya
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Fujita Suguru
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Ueno Sayaka
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Masuda Ken
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Nishisaka Takashi
    Department of Pathology and Laboratory Medicine, Hiroshima Prefectural Hospital, Japan
  • Ishikawa Nobuhisa
    Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan

抄録

<p>A 50-year-old woman presented with left pleural effusion. A pleural fluid cell-block specimen and longitudinal lymph node needle biopsy suggested signet ring cell carcinoma (SRCC). Although computed tomography showed a consolidation shadow in the left lower lobe, a left lung biopsy could not be performed. Upper gastrointestinal endoscopy revealed no malignancies. We administered carboplatin, pemetrexed, ipilimumab, and nivolumab for lung cancer; however, she died due to progressive respiratory failure. Pathological autopsy revealed that the left pleura was thickened as in mesothelioma, based on which pseudomesotheliomatous carcinoma of the lung (PMCL) was diagnosed. PMCLs exhibiting an SRCC morphology are rare. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 63 (7), 979-983, 2024-04-01

    一般社団法人 日本内科学会

参考文献 (13)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ