Pseudomesotheliomatous Carcinoma of the Lung with Morphological Characteristics of Signet Ring Cell Carcinoma: An Autopsy Case Report
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- Hirakawa Tetsu
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Tanimoto Takuya
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Hattori Yui
- Department of Pathology and Laboratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Katsura Ryo
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Miyake Shinya
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Fujita Suguru
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Ueno Sayaka
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Masuda Ken
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Nishisaka Takashi
- Department of Pathology and Laboratory Medicine, Hiroshima Prefectural Hospital, Japan
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- Ishikawa Nobuhisa
- Department of Respiratory Medicine, Hiroshima Prefectural Hospital, Japan
抄録
<p>A 50-year-old woman presented with left pleural effusion. A pleural fluid cell-block specimen and longitudinal lymph node needle biopsy suggested signet ring cell carcinoma (SRCC). Although computed tomography showed a consolidation shadow in the left lower lobe, a left lung biopsy could not be performed. Upper gastrointestinal endoscopy revealed no malignancies. We administered carboplatin, pemetrexed, ipilimumab, and nivolumab for lung cancer; however, she died due to progressive respiratory failure. Pathological autopsy revealed that the left pleura was thickened as in mesothelioma, based on which pseudomesotheliomatous carcinoma of the lung (PMCL) was diagnosed. PMCLs exhibiting an SRCC morphology are rare. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 63 (7), 979-983, 2024-04-01
一般社団法人 日本内科学会