A Case of Pulmonary Cryptococcosis with Laryngeal and Tracheobronchial Lesions

Tsutsumi Masaya, Yamairi Kazushi, Mukai Ayaka, Yamaguchi Mika, Fujii Hiroko, Miki Yuzo, Yagyu Kyoko, Mamoto Takashi, Shoji Seiichi

doi:10.18907/jjsre.46.2_96

Bibliographic Information

Other Title

喉頭，気管気管支に病変を伴った肺クリプトコックス症の1例

Abstract

<p>Background. Cryptococcosis is a deep-seated mycosis caused by a capsular yeast infection with Cryptococcus sp.. Cryptococcus sp. mainly infects the lungs and central nervous system, and laryngeal and tracheal lesions are rare. Case. An 82-year-old woman was diagnosed with Hodgkin lymphoma in January X−3 and achieved a complete response after chemotherapy. Computed tomography (CT) of the chest taken in May X to monitor lymphoma progress revealed a nodular shadow in the lower lobe of the right lung and coughing and hoarseness started simultaneously. Blood tests were positive for Cryptococcus neoformans antigen, and bronchoscopy was performed for a diagnosis. A biopsy of the right S⁶ node and nodular protrusions in the trachea was performed. C. neoformans was culture-positive in the tissue, and cryptococcosis was diagnosed. After treatment with fluconazole, the patient's hoarseness improved, the pulmonary nodular shadow was reduced on chest CT, and bronchoscopy showed improvement of the laryngeal and tracheal lesions. Conclusion. When cryptococcosis is suspected in immunocompetent patients, it is important to check for bronchial and laryngeal lesions.</p>

Journal

The Journal of the Japan Society for Respiratory Endoscopy

The Journal of the Japan Society for Respiratory Endoscopy 46 (2), 96-101, 2024-03-25

The Japan Society for Respiratory Endoscopy

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Details 詳細情報について

CRID: 1390299673820435840

DOI: 10.18907/jjsre.46.2_96

ISSN: 21860149; 02872137

Text Lang: ja

Data Source

JaLC

Abstract License Flag: Disallowed

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