Summary of 30 Cases of Introduction of Hydroxychloroquine for Lupus Erythematosus at the Department of Dermatology, Asahikawa Medical University
-
- Nozaki Hiroyoshi
- Department of Dermatology, Asahikawa Medical University
-
- Kishibe Mari
- Department of Dermatology, Asahikawa Medical University
-
- Kanno Kyoko
- Department of Dermatology, Asahikawa Medical University
-
- Igawa Satomi
- Department of Dermatology, Asahikawa Medical University
-
- Honma Masaru
- Center for Promotion of International Exchange, Asahikawa Medical University
-
- Chuma Masayuki
- Department of Pharmacy, Asahikawa Medical University Hospital
-
- Tasaki Yoshikazu
- Department of Pharmacy, Asahikawa Medical University Hospital
-
- Yamamoto Akemi
- Department of Dermatology, Asahikawa Medical University
Bibliographic Information
- Other Title
-
- 旭川医科大学皮膚科でエリテマトーデスに対してヒドロキシクロロキンを導入した30症例のまとめ
Abstract
<p>The efficacy and safety of hydroxychloroquine (HCQ) were evaluated in 30 patients (CLE 18 cases, SLE 18 cases) with cutaneous lupus erythematosus and systemic lupus erythematosus who were introduced to it at our department. Their ages ranged from 19 to 80 years (median age 48). Four cases were male, 26 cases were female. In terms of efficacy, the Cutaneous Lupus erythematosus disease Area and Severity Index activity score (CLASI) and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) were significantly reduced; 60% of patients receiving concomitant prednisolone were able to reduce their prednisolone dose after HCQ induction. In terms of safety, due to adverse events, HCQ was discontinued in 9 patients, of whom 4 were diagnosed with drug eruptions and only 1 was able to resume the drug. Although three patients received more than 6.5 mg/kg/day of HCQ per actual body weight, none of them developed retinopathy.</p>
Journal
-
- The Japanese Journal of Dermatology
-
The Japanese Journal of Dermatology 134 (4), 733-741, 2024-04-20
Japanese Dermatological Association
- Tweet
Details 詳細情報について
-
- CRID
- 1390299903955989888
-
- ISSN
- 13468146
- 0021499X
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
-
- Abstract License Flag
- Disallowed