Outcomes of Transcatheter Closure of Congenital Left Circumflex Coronary Artery Fistula
-
- Wei Peijian
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Fang Fang
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Zhang Fengwen
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Li Yihang
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Kong Pengxu
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Feng Shuyi
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Xu Zhongying
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Xu Liang
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Wan Junyi
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Zhang Gejun
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
-
- Pan Xiangbin
- Department of Structural Heart Disease, National Center for Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences Peking Union Medical College
Abstract
<p>Background: Congenital left circumflex coronary artery fistula (LCX-CAF) is a relatively rare type of coronary artery fistula (CAF); little is known about the outcomes of transcatheter closure (TCC) of LCX-CAF.</p><p>Methods and Results: All consecutive patients admitted to Fuwai Hospital and scheduled for TCC of LCX-CAF between January 2012 and December 2022 were reviewed retrospectively. Of the 25 consecutive patients (mean [±SD] age 34±20 years; 48% male) admitted and scheduled for TCC of congenital LCX-CAF, the procedure was feasible in 22 (77.3%). The mean (±SD) diameter of the fistulas was 6.99±2.04 mm; 21 (84%) patients had a large fistula (i.e., diameter >2-fold greater than non-feeding coronary artery). Occluders were deployed via a transarterial approach and arteriovenous loop in 6 (27.3%) and 16 (72.7%) patients, respectively. No procedural complications were recorded. Although the procedural success rates are similar for single LCX-CAF and left anterior descending CAF (81.25% vs. 92.86%; P=0.602), the mean time from initial angiography to first occluder deployment is significantly longer for LCX-CAF (83.06±36.07 vs. 36.00±9.49 min; P<0.001). The mean (±SD) follow-up time was 62.2±45.5 months. The incidence of myocardial infarction and recanalization of the fistula was 4.5% (1/22) and 9.1% (2/22), respectively.</p><p>Conclusions: TCC of LCX-CAF is a feasible and effective alternative to surgical repair, with comparable outcomes in selected patients. Optimal medical therapy to prevent post-closure myocardial infarction requires further investigation.</p>
Journal
-
- Circulation Journal
-
Circulation Journal advpub (0), 2024-05-09
The Japanese Circulation Society