心エコー検査による生体肝移植術後難治性腹水の術前リスク評価
書誌事項
- タイトル別名
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- The impact of echocardiography on predicting refractory ascites following living-donor liver transplantation
説明
<p>【Objective】 Postoperative prolonged ascites is a common complication after living-donor liver transplantation (LDLT). However, there is little evidence regarding the circulatory indicators as risk factors for ascites after LDLT. The aim was to evaluate the impact of trans tricuspid pressure gradient (TRPG) on postoperative prolonged ascites.</p><p>【Design】 Case-series.</p><p>【Method】 We collected data from 268 recipients who underwent LDLT for liver failure between 2008 and 2022. We excluded 7 recipients who died within 30 days after LDLT and divided the remainer into two groups by TRPG value.</p><p>【Results】 Of the 261 patients with liver failure, 98 (37.7%) were classified as the high TRPG group and 163 (62.3%) comprised the low TRPG group. There was a significant difference in the rate of intractable ascites between the two groups, but no significant difference in overall survival (OS). After PSM, univariate analysis detected two risk factors, high TRPG value and ascites at laparotomy ≥5000 mL. In the multivariate analysis, high TRPG value (P=0.0345, OR=11.4, 95% CI 1.19-108) and ascites at laparotomy ≥5000 (mL) (P=0.0067, OR=10.2, 95% CI 1.91-54.8) were identified as independent risk factors.</p><p>【Conclusion】 Preoperative TRPG elevation is a risk for prolonged ascites after LDLT, and it can be valuable to measure TRPG in the preoperative condition assessment.</p>
収録刊行物
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- 移植
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移植 59 (1), 37-42, 2024
一般社団法人 日本移植学会
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詳細情報 詳細情報について
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- CRID
- 1390300755743388416
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- ISSN
- 21880034
- 05787947
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可