Cell Therapy for Ischemic Stroke : Status and Prospects

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  • 虚血性脳血管障害に対する幹細胞治療の多様性
  • ―現状と展望―

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<p>  Substantial contributions has made to improve the functional prognosis and reduce mortality rates through advances in medical treatment of ischemic cerebrovascular disease, such as alteplase and tenecteplase during the acute phase, development of cerebrovascular surgery, strengthening of regional cooperation, and standardization of treatment. However, in an aging society, it remains the leading cause of being bedridden due to the influence of underlying diseases, frailty, and the social environment, and is a major factor in rising healthcare costs. The treatment of cerebrovascular disease involves three phases : preventive, acute phase, and chronic phase therapy. Future studies should aim for the development of new treatments for the subacute to chronic phase. Regarding stem cell therapy after cerebral infarction, many basic research reports, clinical trials, and studies are underway or completed worldwide. Here, we review the basic experiments, clinical trials, and studies of stem cell therapy for ischemic cerebrovascular disease and consider future prospects.</p>

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