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Interstitial Pneumonia Associated with Nodal T-follicular Helper Cell Lymphoma
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- Nakamura Satoshi
- Department of Respiratory Medicine, Kyushu University Hospital, Japan
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- Takano Tomotsugu
- Department of Respiratory Medicine, Kyushu University Hospital, Japan
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- Nakatsuru Kousei
- Department of Respiratory Medicine, Kyushu University Hospital, Japan
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- Tsubouchi Kazuya
- Department of Respiratory Medicine, Kyushu University Hospital, Japan
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- Yamauchi Takuji
- Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Japan
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- Okamoto Isamu
- Department of Respiratory Medicine, Kyushu University Hospital, Japan
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- Hashisako Mikiko
- Division of Diagnostic Pathology, Kyushu University Hospital, Japan
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- Iwasaki Takeshi
- Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Japan
Bibliographic Information
- Published
- 2024-12-01
- Resource Type
- journal article
- DOI
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- 10.2169/internalmedicine.3601-24
- Publisher
- The Japanese Society of Internal Medicine
Search this article
Description
<p>Nodal T-follicular helper cell lymphoma (nTFHL), a hematologic neoplasm originating from T-follicular helper (TFH) cells, occasionally presents with pulmonary radiographic abnormalities, without neoplastic cellular infiltration. However, the precise mechanisms underlying non-neoplastic pulmonary opacities in patients with nTFHL remain unclear. Previous reports have shown that TFH cell abnormalities are associated with collagen disease and interstitial pneumonia with autoimmune features (IPAF). We herein report a patient with nTFHL accompanied by interstitial pneumonia diagnosed via lung and lymph node biopsies. These findings suggest the need to rule out nTFHL before diagnosing IPAF. </p>
Journal
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- Internal Medicine
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Internal Medicine 63 (23), 3227-3231, 2024-12-01
The Japanese Society of Internal Medicine
